Cancer ameliorating potential of Phyllanthus amarus: In vivo and in vitro studies against Aflatoxin B1 toxicity

Efficacy of Silybum Marianum Seeds in Ameliorating the Toxic Effects of Aflatoxin B1 in Broilers

Background: This study aims to evaluate the efficacy of silybum marianum seeds (SMSs) on blood biochemical profile of broiler chickens contaminated with Aflatoxin B1 (AFB1).  Methods: Combinations of three levels of AFB1 (0, 250 and 500 ppb) with three levels of SMSs (0, 0.5, and 1.0 %) were incorporated into the basal diet (corn and soybean meal). The effect of nine experimental treatments was...

Antioxidant Potential of Aegle marmelos Leaves Against Aflatoxin B1 Induced Liver Toxicity in Rats

Aegle marmelos leaves have been used for treatment of various liver aliments from time immemorial. Pre-treatment of A.marmelos leaves crude powder at its therapeutic dose (1000 mg/kg body weight) was carried out to determine the efficacy on aflatoxin B1 (AFB1) (1 mg/kg body weight) induced liver toxicity in rats. The crude powder of A.marmelos was found to be a potent inducer of the phase II de...

Somoclonal Variation Studies on Phyllanthus amarus Schum & Thonn

The present study was aimed at the development of a somoclonal variant and isozyme marker for Phyllanthus amarus Schum & Thonn using inter-nodal segments and the enzyme peroxidase. Maximum callus proliferation was obtained on Murashige and Skoog’s medium supplemented (MS) with 1.0 mg/l of 2,4-Dichlorophenoxyacetic acid. Three weeks-old pale yellowish white semi-friable callus was used for organ...

Phyllanthus Amarus: A Review

Herbs have always formed an integral part of human health and are used in the treatment of several human diseases. One of such species which have wide patronage of use is Phyllanthus amarus. This herb is in traditional medicine for more than 3,000 years. The plant has also served as lead for several experimental investigations that explored its phytochemical constituents and pharmacological use...

Anti Oxidative, Anti Peroxidative and Hepatoprotective Potential of Phyllanthus amarus Against Anti Tb Drugs